CORTICET SHOCK X 10 CC

CORTICET SHOCK X 10 CC

CORTICET SHOCK X 10 CC

Dexamethasone 21 phosphate is a fluorinated corticoid of 2nd. generation of very fast action and that reduces the inflammatory response through the inhibition of prostaglandin synthesis, stabilizing the lysosomal membranes, reducing the release of enzymes and inhibiting the migration of inflammatory cells (neutrophils and monocytes-macrophages), as well as decreases the ability to release histamine by basophils and mast cells. It also reduces the release of toxic metabolites from oxygen and inhibits the synthesis and secretion of chemotaxins (interleukin I). These properties make it the drug of choice for all those acute inflammatory processes that may or may not compromise the animal’s life.

Because more than 80% of the drug circulates bound to plasma proteins, a reduction of them, mainly transcortin, increases the susceptibility to the effects of glucocorticoids.

It has a direct positive inotropic effect on the heart and vessels increases the reactivity to the catecholamines and inhibits the Nitric Oxide Synthase (NOS) vascular producing an increase in blood pressure.

In cases of shock, whether hypovolemic, traumatic, hemorrhagic or septic, the use of this drug associated with the corresponding fluid therapy and the application of epinephrine is recommended.

CORTICET SHOCK X 10 CC

 

INDICATIONS OF USE

It is indicated for shock, stress, Neonatal Disorder Syndrome, traumatic brain injury, spinal cord compressions, bronchospasm, allergic reactions and for all those acute inflammations of the locomotor system.

 

ROUTES OF ADMINISTRATION AND DOSES

Although all routes of administration are available, the route of choice is intravenous, since it allows a rapid bioavailability of the drug.

It is advisable to administer from 0.2 to 0.8 mg / kilo of weight and 2 mg / kilo of weight in cases of shock. In the latter case, repeat at 3 and 6 o’clock.

 

CONTRAINDICATIONS

In cases where a circulatory disorder is suspected at the capillary circulation level, do not use or use it under strict control because it favors the thrombotic processes.

 

WARNINGS

Keep the product in a clean, dry place and out of the reach of children, between 4º and 30º C.

Veterinary use.

CORTICET SHOCK X 10 CC

PRESENTATION

Vial for 10 ml. of sterile injectable solution.

Cortivet Shock Formula

 

amounts

Dexamethasone 21 Phosphate

200 mg

Formulation agents csp

10 ml

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